Updates for April 2013

April 30, 2013. Added a new line to the Links section on the right:
DIY Research: [Lifehacker] [Bradford Hill Criteria]

Updates for March 2013

March 31, 2013. In Prostate Cancer Calculators the description of the calculators on the SWOP site has been revised and the site has been moved into our list of comprehensive calculators. See this description of the calculators or this link to use the calculators.

Updates for February 2013

February 28, 2013. High Fiber Diet. Research on mice has found that a high fiber diet (believed to be due to the active ingredient inositol hexaphosphate, also known as IP6) can slow progression of prostate cancer in mice. See [US Too 3/2013 pg. 5] and [PMID: 23213071]. It is unknown whether this applies to humans. The American Cancer Society summarizes what is known [here]. A set of slides on high fiber foods is available on [WedMB].

Updates for January 2013

Jan 31, 2013. In Inguinal Hernia and Prostatectomy: According a 2012 article in the Wall Street Journal "More than 30% of patients may suffer from long-term chronic pain and restricted movement after surgery to fix a hernia". A Free iPhone App to forecast pain after hernia operations is available.

Updates for December 2012

Dec 1, 2012. In Biochemical PSA Recurrence we added: A randomized trial [PMID: 23162860"] which followed subjects a median 11.2 years found an 8% reduction in cancers among men who took daily multivitamins. An article on page 3 of UStoo newsletter discusses it further. The author points out that although the reduction is modest the fact that its a randomized study rather than observational makes it more reliable. He indicates that the multivitamins used are most similar to children's multivitamins and the actual brand they used currently has a different formulation so that cannot be used to ensure comparability.

Blog updates for November 2012

Nov 6, 2012. In Biochemical PSA Recurrence we added: Anti-Angiogenesis. As solid tumors require supporting blood vessels to grow many years ago Judah Folkman [papers] proposed that one way to combat cancer might be to prevent the growth of blood vessels. About a dozen drugs having this effect are already on the market for other cancers (breast, lung, colon, brain, and kidney) but none for prostate cancer. See [PMID: 20678204] for a review. In a [TED video] Dr. William Li speculates on the possibility that if applied early enough that simply eating foods known to inhibit angiogenesis might prevent cancer or recurrence. See the list of foods [here].

Blog updates for October 2012

Oct 31, 2012. In PSADT Part 1 we add: In a [2010 thesis by E. Mehrara] it is pointed out that statistical analysis of doubling times is complicated by its typically skewed distribution and that its reciprocal (1/PSADT) is more symmetric which is more consistent with many statistical procedures. Equation (10) of that thesis suggests the use of ln(2)/PASDT since that numerically equals the constant in the differential equation of exponential growth. (Also see [PMID:1744013] [Full Text]).

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Oct 4, 2012. In WCRF/AICR Diet and Cancer Report we added: It is expected that upcoming udpates will be available in 2013 on endometrial and ovarian cancers and on breast cancer survivors and in 2014 on cancers of prostate, bladder, kidney, liver and gallbladder. WCRF/AICR Timetable.