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Sunday, February 4, 2007

Elevated uPA and uPAR in aggressive cancer

In a small scale study, Dallas researchers have found that elevated levels of urokinase-typeplasminogen activator (uPA) and its soluble receptor (uPAR) are associated with (1) features of biologically aggressive prostate cancer and disease progression after radical prostatectomy and (2) metastasis. J Clin Oncol. 2007 Feb 1. 25(4):349-55. [PMID: 17264329]

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